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© 1960 Oxford University Press

RESEARCH-ARTICLE

Some Enzymic Steps in the Metabolism of Serine and Glycine by Higher Plants

I. HYDROXYMETHYL TETRAHYDROFOLIC DEHYDROGENASE FROM TURNIPS

A. P. WILKINSON and D. D. DAVIES

Botany Department, King's: College London

The presence of the enzyme hydroxymethyl tetrahydrofolic dehydrogenase has been demonstrated in cell-free preparations from turnip hypocotyls. The enzyme is specific for triphosphopyridine nucleotide and, in conjunction with the enzyme serine aldolase, converts the hydroxymethyl group of serine into the formyl group of N10 formyl tetrahydrofolic acid. N10 formyl tetrahydrofolic acid formed enzymically from serine-3-14C was converted to anhydroleucovorin and isolated by chromatography.


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