Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (28)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Hefner, E.
Right arrow Articles by Britt, A. B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hefner, E.
Right arrow Articles by Britt, A. B.
Agricola
Right arrow Articles by Hefner, E.
Right arrow Articles by Britt, A. B.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Journal of Experimental Botany, Vol. 54, No. 383, pp. 669-680, February 1, 2003
© 2003 Oxford University Press

Arabidopsis mutants sensitive to gamma radiation include the homologue of the human repair gene ERCC1

Received 16 July 2002; Accepted 2 October 2002

E. Hefner2, S. B. Preuss1 and A. B. Britt3,1

1 Department of Plant Biology, University of California, Davis, Davis, CA 95616, USA
2 Genetics Graduate Group, Department of Plant Biology, University of California, Davis, Davis, CA 95616, USA

3 To whom correspondence should be addressed. E-mail: abbritt{at}ucdavis.edu

Mutants sensitive to ionizing radiation in yeast and mammals include an assortment of DNA repair genes. The majority of these DNA repair genes are involved in the repair of DNA double-strand breaks. In this study a forward genetic screen is used to identify {gamma}-sensitive mutants of Arabidopsis thaliana. The {gamma}-plantlet screen used here also reveals two general mutant classes based on size of cotyledons and hypocotyls. One of the mutants discovered is a homologue of the mammalian nucleotide excision repair gene ERCC1.

Key words: Arabidopsis, DNA repair, double-strand breaks, ERCC1, ionizing radiation sensitive, Rad10, UV.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Proc. Natl. Acad. Sci. USAHome page
K. Yoshiyama, P. A. Conklin, N. D. Huefner, and A. B. Britt
Suppressor of gamma response 1 (SOG1) encodes a putative transcription factor governing multiple responses to DNA damage
PNAS, August 4, 2009; 106(31): 12843 - 12848.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
B. A. Kunz, P. K. Dando, D. M. Grice, P. G. Mohr, P. M. Schenk, and D. M. Cahill
UV-Induced DNA Damage Promotes Resistance to the Biotrophic Pathogen Hyaloperonospora parasitica in Arabidopsis
Plant Physiology, October 1, 2008; 148(2): 1021 - 1031.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
A. Ahmad, A. R. Robinson, A. Duensing, E. van Drunen, H. B. Beverloo, D. B. Weisberg, P. Hasty, J. H. J. Hoeijmakers, and L. J. Niedernhofer
ERCC1-XPF Endonuclease Facilitates DNA Double-Strand Break Repair
Mol. Cell. Biol., August 15, 2008; 28(16): 5082 - 5092.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
M. Klutstein, H. Shaked, A. Sherman, N. Avivi-Ragolsky, E. Shema, D. Zenvirth, A. A. Levy, and G. Simchen
Functional Conservation of the Yeast and Arabidopsis RAD54-Like Genes
Genetics, April 1, 2008; 178(4): 2389 - 2397.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
F. Hartung, S. Suer, T. Bergmann, and H. Puchta
The role of AtMUS81 in DNA repair and its genetic interaction with the helicase AtRecQ4A
Nucleic Acids Res., September 11, 2006; 34(16): 4438 - 4448.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
H. Shaked, N. Avivi-Ragolsky, and A. A. Levy
Involvement of the Arabidopsis SWI2/SNF2 Chromatin Remodeling Gene Family in DNA Damage Response and Recombination
Genetics, June 1, 2006; 173(2): 985 - 994.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
A. J. Wijeratne, C. Chen, W. Zhang, L. Timofejeva, and H. Ma
The Arabidopsis thaliana PARTING DANCERS Gene Encoding a Novel Protein Is Required for Normal Meiotic Homologous Recombination
Mol. Biol. Cell, March 1, 2006; 17(3): 1331 - 1343.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
J. D. Friesner, B. Liu, K. Culligan, and A. B. Britt
Ionizing Radiation-dependent {gamma}-H2AX Focus Formation Requires Ataxia Telangiectasia Mutated and Ataxia Telangiectasia Mutated and Rad3-related
Mol. Biol. Cell, May 1, 2005; 16(5): 2566 - 2576.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
S. Kimura, Y. Tahira, T. Ishibashi, Y. Mori, T. Mori, J. Hashimoto, and K. Sakaguchi
DNA repair in higher plants; photoreactivation is the major DNA repair pathway in non-proliferating cells while excision repair (nucleotide excision repair and base excision repair) is active in proliferating cells
Nucleic Acids Res., May 18, 2004; 32(9): 2760 - 2767.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
K. Culligan, A. Tissier, and A. Britt
ATR Regulates a G2-Phase Cell-Cycle Checkpoint in Arabidopsis thaliana
PLANT CELL, May 1, 2004; 16(5): 1091 - 1104.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
S. B. Preuss and A. B. Britt
A DNA-Damage-Induced Cell Cycle Checkpoint in Arabidopsis
Genetics, May 1, 2003; 164(1): 323 - 334.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.