Skip Navigation



JXB Advance Access published online on December 12, 2007
Journal of Experimental Botany, doi:10.1093/jxb/erm239
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
59/3/501    most recent
erm239v1
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Mur, L. A. J.
Right arrow Articles by Prats, E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mur, L. A. J.
Right arrow Articles by Prats, E.
Agricola
Right arrow Articles by Mur, L. A. J.
Right arrow Articles by Prats, E.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author [2007]. Published by Oxford University Press [on behalf of the Society for Experimental Biology]. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

REVIEW ARTICLE

The hypersensitive response; the centenary is upon us but how much do we know?

Luis A. J. Mur1,*, Paul Kenton1, Amanda J. Lloyd1, Helen Ougham2 and Elena Prats3

1University of Wales Aberystwyth, Institute of Biological Sciences, Aberystwyth, Ceredigion SY23 2DA, UK
2Institute of Grassland and Environmental Research, Plas Gogerddan, Aberystwyth, Ceredigion SY23 3EB, UK
3Instituto de Agricultura Sostenible IAS-CSIC, Alameda del Obispo Apdo 4084, Córdoba 14080, Spain

* To whom correspondence should be addressed. E-mail: lum{at}aber.ac.uk

With the centenary of the first descriptions of ‘hypersensitiveness’ following pathogenic challenge upon us, it is appropriate to assess our current understanding of the hypersensitive response (HR) form of cell death. In recent decades our understanding of the initiation, associated signalling, and some important proteolytic events linked to the HR has dramatically increased. Genetic approaches are increasingly elucidating the function of the HR initiating resistance genes and there have been extensive analyses of death-associated signals, calcium, reactive oxygen species (ROS), nitric oxide, salicylic acid, and now sphingolipids. At the same time, attempts to draw parallels between mammalian apoptosis and the HR have been largely unsuccessful and it may be better to consider the HR to be a distinctive form of plant cell death. We will consider if the HR form of cell death may occur through metabolic dysfunction in which malfunctioning organelles may play a major role. This review will highlight that although our knowledge of parts of the HR is excellent, a comprehensive molecular model is still to be attained.

Key words: Hypersensitive response, pathogen, programmed cell death, resistance

Received 12 July 2007; Revised 22 August 2007 Accepted 30 August 2007


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J Exp BotHome page
S. M. Doyle, M. Diamond, and P. F. McCabe
Chloroplast and reactive oxygen species involvement in apoptotic-like programmed cell death in Arabidopsis suspension cultures
J. Exp. Bot., November 20, 2009; (2009) erp320v1.
[Abstract] [Full Text] [PDF]

Home page
 J Exp BotHome page
J. P. Klingler, R. M. Nair, O. R. Edwards, and K. B. Singh
A single gene, AIN, in Medicago truncatula mediates a hypersensitive response to both bluegreen aphid and pea aphid, but confers resistance only to bluegreen aphid
J. Exp. Bot., October 1, 2009; 60(14): 4115 - 4127.
[Abstract] [Full Text] [PDF]

Home page
 Mol PlantHome page
I. Pandelova, M. F. Betts, V. A. Manning, L. J. Wilhelm, T. C. Mockler, and L. M. Ciuffetti
Analysis of Transcriptome Changes Induced by Ptr ToxA in Wheat Provides Insights into the Mechanisms of Plant Susceptibility
Mol Plant, September 1, 2009; 2(5): 1067 - 1083.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
D. Salomon, A. Bonshtien, M. Mayrose, C. Zhang, K. M. Shokat, and G. Sessa
Bypassing Kinase Activity of the Tomato Pto Resistance Protein with Small Molecule Ligands
J. Biol. Chem., May 29, 2009; 284(22): 15289 - 15298.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
J. Scharte, H. Schon, Z. Tjaden, E. Weis, and A. von Schaewen
Isoenzyme replacement of glucose-6-phosphate dehydrogenase in the cytosol improves stress tolerance in plants
PNAS, May 12, 2009; 106(19): 8061 - 8066.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.